Whole blood histamine is a lab test and an important marker for methylation levels and we can use it to determine over or under methylators. People with high histamine are undermethylators and individuals with low histamine are overmethylators.
People who are undermethyled tend to have lower activity of serotonin, dopamine and norepinephrine. These are important neurotransmitters making the person prone to depression, OCD, Autism.
There are others that can be overmethylated. These people tends to have high levels of serotonin, dopamine and epinephrine. This increase in the neurotransmitter can make them prone to symptoms of anxiety, pain, insomnia, bipolar and paranoid schizophrenia.
Methylation is extremely important because if you have a methylation disorder it can alter several genes by turning them on or silencing them.
For instance, we know that the DAO gene is responsible for the breakdown of histamine. If we are not breaking down the histamine in our body, this will lead to high histamine levels making this person prone to undermethylation type symptoms such as anxiety and insomnia.
Overmethylation: General Characteristics
- High anxiety
- Sleep Disorders
- Food and chemical sensitivities
- Absences of seasonal allergies
- Dry eyes and mouth
- High Artistic qualities
- Adverse reaction to SSRI medication
- Improvement after Benzodiazapines
- Nervous legs
- Underachiever in school
Generally, these people improve with folate therapy.
Undermethylation: General Characteristics
- Depression due to low serotonin
- Addictive tendencies; OCD
- Good Response to SSRIâ€™s
- Self motivate, very competitive
- Over achievers
- Low tolerance for pain
This group often shows a low level of methyl or SAMe, which donates methyl. To correct this, it is important to look at SAMe and Histamine levels to see where we need to supplement.
When we determine there is a need for supplementation we recommend Histamine Block from Seeking Health.
“Within the first 10 days of therapy, which was only four treatments, I noticed a major decrease in my pain level. After about 10 sessions, my pain level diminished to hardly noticeable. I am very thankful for the treatment program because it saved my career and increased my quality of life more than I could have ever imagined.”â€‹
“Dr. Michael Veselak and his spinal decompression clinic have changed my life in a way I never would have thought possible. Now, five weeks after I started my treatment, I’m back to my very active lifestyle. During my entire treatment, I’ve been completely medication free. I couldn’t have done it without Dr. Veselak. I would highly recommend this treatment to anyone faced with surgery as their only option or people that have chronic neck and/or back pain. This is an option you cannot afford to pass up.”
Chronic Pain Testimonial
Chronic Pain Testimonial
[contact-form-7 404 "Not Found"]